Current Position, Affiliation
- Associate Professor, Division of Nephrology and Endocrinology, The University of Tokyo Graduate School of Medicine, Japan
Education / Training
- 1996, M.D., The University of Tokyo
- 2003, PhD., The University of Tokyo
Professional and Research Experience
- 2004 - 2014, Assistant Professor, Division of Nephrology and Endocrinology, The University of Tokyo Hospital
- 2014 - 2017, Assistant Professor, The University of Tokyo Health Service Center
- 2015 - 2019, Lecturer, Division of Nephrology and Endocrinology, The University of Tokyo Hospital
- 2019 - Present, Associate Professor, Division of Nephrology and Endocrinology, The University of Tokyo Graduate School of Medicine
Awards & Honors
- 2002, Young Investigator Award, Japan Endocrine Society
- 2007, 1st Award, Gordon Research Conference（Molecular Pharmacology）
- 2013, Research Encouragement Award, Japan Endocrine Society
Selected Publications
- Sato J, Manaka K, Horikoshi H, Taguchi M, Harada K, Tsuboi T, Nangaku M, Iiri T, and Makita N. Insights into GLP-1 and insulin secretion mechanisms in pasireotide-induced hyperglycemia highlight effectiveness of Gs-targeting diabetes treatment. Sci Rep. 15(1):9494, 2025
- Makita N., Sato J, Manaka K, Akahane K, Ito T, Yamazaki H, Mizoguchi A, Hikima Y, Horikoshi H, Nangaku M, and Iiri T. Successful prednisolone or calcimimetic treatment of acquired hypocalciuric hypercalcemia caused by biased allosteric autoantibodies JCI Insight. 7(20):e156742, 2022
- Makita N, Ando T, Sato J, Manaka K, Mitani K, Kikuchi Y, Niwa T, Ootaki M, Takeba Y, Matsumoto N, Kawakami A, Ogawa T, Nangaku M, and Iiri T. Cinacalcet corrects biased allosteric modulation of CaSR by AHH autoantibody. JCI Insight. 4(8):e126449, 2019
- Makita N, Sato J, Yajima-Shoji Y, Manaka K, Eda-Hashimoto M, Ootaki M, Matsumoto N, Nangaku M and Iiri T. Analysis of V2 vasopressin receptor (V2R) mutations causing partial nephrogenic diabetes insipidus highlights a sustainable signaling by a non-peptide V2R agonist. J. Biol. Chem. 291: 22460-71, 2016.
- Makita N. Kabasawa Y. Otani,Y Firman, Sato J. Hashimoto M. Nakaya M. Nishihara H. Nangaku M. Kurose H. Ohwada T. and Iiri T. Attenuated desensitization of beta-adrenergic receptor by water-soluble N-nitrosamines that induce S-nitrosylation without NO release Circ Res. 112 327-34, 2013
Update on Electrolyte Imbalance Disorders
Role
Speaker
Date & Time
12/05 14:15 - 14:30
Place
Room 2 ( 701B )
Lecture Title
Divalent Cation Disorders