Current Position, Affiliation
- Senior Investigator, Epithelial Systems Biology Laboratory, NHLBI, NIH, Bethesda USA
Education / Training
- 1970, B.S, Chemical Engineering, University of Michigan
- 1975, PhD., Biomedical Engineering, Case Western Reserve University
- 1976, M.D., Case Western Reserve University
Professional and Research Experience
- 1988 - 2009, Senior Investigator, Laboratory of Kidney and Electrolyte Metabolism, NHLBI, DIR, NIH
- 2009 - Present, Senior Investigator, Epithelial Systems Biology Laboratory, NHLBI, DIR, NIH
Awards & Honors
- 2001, Homer W. Smith Award, American Society of Nephrology
- 2008, Donald W. Seldin Lectureship of the American Heart Association
- 2012, Hugh Davson Distinguished Lectureship of the American Physiological Society
- 2014, Robert W. Berliner Award for Excellence in Renal Physiology, American Physiological Society
- 2017, Steven B. Hebert Award, Epithelial Transport Group, American Physiological Society,
Selected Publications
- Knepper MA, Kwon TH, Nielsen S. Molecular physiology of water balance. N Engl J Med. 2015;372(14):1349-58
- Isobe K, Jung HJ, Yang CR, Claxton J, Sandoval P, Burg MB, Raghuram V, Knepper MA. Systems-level identification of PKA-dependent signaling in epithelial cells. Proc Natl Acad Sci U S A. 2017;114(42):E8875-E8884.
- Sung CC, Chen L, Limbutara K, Jung HJ, Gilmer GG, Yang CR, Lin SH, Khositseth S, Chou CL, Knepper MA. RNA-Seq and protein mass spectrometry in microdissected kidney tubules reveal signaling processes initiating lithium-induced nephrogenic diabetes insipidus. Kidney Int. 2019;96(2):363-377.
- Chen L, Chou CL, Knepper MA. A Comprehensive Map of mRNAs and Their Isoforms across All 14 Renal Tubule Segments of Mouse. J Am Soc Nephrol. 2021;32(4):897-912.
- Kikuchi H, Chou CL, Yang CR, Chen L, Jung HJ, Park E, Limbutara K, Carter B, Yang ZH, Kun JF, Remaley AT, Knepper MA. Signaling mechanisms in renal compensatory hypertrophy revealed by multi-omics. Nat Commun. 2023;14(1):3481.
Plenary Lecture 3
Role
Speaker
Date & Time
12/06 08:30 - 09:20
Place
Room 1 ( 701A )
Lecture Title
Aquaporin-2 in the Physiology and Pathophysiology of Water Balance