Current Position, Affiliation
- Director, Department of Medical Research, Taipei Medical University Hospital, Taipei, Taiwan
- Director, Department of Internal Medicine, Taipei Medical University Hospital, Taiwan
- Chair, International Affairs and Cooperation Committee, Taiwan Society Nephrology.
- Deputy Chair, Diversity and Equity Committee, Asian Pacific Society of Nephrology
- Member, North and East Asia Regional Board, International Society of Nephrology
Education / Training
- 1998, M.D., College of Medicine, University of Buenos Aires, Argentina (Summa Cum Laude)
Professional and Research Experience
- 2011 - Present, Principal Investigator, National Science and Technology Council Projects
- 2023 - Present, Principal Investigator, Precision Medicine for Kidney Disease, Taipei Medical University
- 2024 - Present, National Lead, A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Povetacicept in Adults with Immunoglobulin A Nephropathy (RAINIER)
- 2025 - Present, National Lead, n Open-label, Multicenter, Randomized Phase 3 Study Evaluating the Efficacy and Safety of Felzartamab in Subjects with Primary Membranous Nephropathy (PMN)-PROMINENT study.
- 2025 - Present, National Lead, 22). A Phase 2 Study to Assess ADX-038 in Participants With Complement-Mediated Kidney Disease
Awards & Honors
- 2024, Silver Medal Presentation Award. Taiwan Society of Internal Medicine.
- 2023, Gold Medal Award, Outstanding paper. Taiwan Clinical Dialysis Association.
- 2022, Best poster presentation award. Taiwan Society Nephrology
- 2022, Gold Medal Award, Outstanding paper. Taiwan Clinical Dialysis Association
- 2022, FutureTech Award, Ministry of Science and Technology, Taiwan
Selected Publications
- Wu IW, Gao SS, Chou HC, Yang HY, Chang LC, Kuo YL, Dinh MCV, Chung WH, Yang CW, Lai HC, Hsieh WP, Su SC*. Integrative metagenomic and metabolomic analyses reveal severity-specific signatures of gut microbiota in chronic kidney disease. Theranostics. 2020, 10(12), 5398-5411.
- Wu IW, Tsai TH, Lo CJ, Chou YJ, Yeh CH, Cheng ML, Lai CC*, Sytwu HK*, Tsai TF*. Discovery of a Biomarker Signature that Reveals a Molecular Mechanism Underlying Diabetic Kidney Disease via Organ Crosstalk. Diabetes Care. 2022; 45(6):e102-e104
- Wu IW, Tsai TH, Lo CJ, Chou YJ, Yeh CH, Chan YH, Chen JH, Hsu PW, Pan HC, Hsu HJ, Chen CY, Lee CC, Shyu YC, Lin CL, Cheng ML, Lai CC*, Sytwu HK*, Tsai TF*. Discovering a trans-omics biomarker signature that predisposes high risk diabetic patients to diabetic kidney disease. NPJ Digit Med. 2022;2;5(1):166.
- Wu, I W, Liao Y C, Tsai TH, Lin CH, Shen ZQ, Chan YH, Tu CW, Chou YJ, Lo CJ, Yeh CH, Chen CY, Pan HC, Hsu HJ, Lee CC, Cheng ML, Sheu WHH, Lai CC, Sytwu HK & Ting-Fen Tsai. Machine-learning assisted discovery unveils novel interplay between gut microbiota and host metabolic disturbance in diabetic kidney disease. Gut Microbes, 2025, 17(1), 2473506.
- Lin MR*, Wu IW*, Chou WH1, Lin YF, Hung KY, Kaname Kojima, Kosuke Shido, Kengo Kinoshita, Chang WC and Mai-Szu Wu. Whole Exome Sequencing and Polygenic Risk Assessment for Kidney Functions and Clinical Management in both Hospital-Based Cohort and Population-Based Asian Cohorts. J Biomed Sci. 2025 Aug 6;32(1):72. (Co-first author).
Gut Microbiome and Metabolomics in CKD
Role
Moderator
Date & Time
12/05 13:30 - 14:45
Place
Room 1 ( 701A )
APSN DEC session: Diversity and Equity in Kidney Care
Role
Moderator
Date & Time
12/05 16:10 - 17:40
Place
Room 5 ( 701G )
Microbiota and Cardiovascular - Kidney- Metabolic (CKM) Syndrome
Role
Speaker
Date & Time
12/07 11:10 - 11:25
Place
Room 3 ( 701C )
Lecture Title
Role of Bacteroides on Host Inflammation and Metabolism in CKM
Sponsored by GSK
Role
Speaker
Date & Time
12/07 12:30 - 13:30
Place
Room 7 ( 703 )
Lecture Title
Bridging Risk and Prevention: Shingles Management Insights for Nephrologists